Dalriada Wordmark

Join Us​

Help discover small molecule therapies that could change the world​

Who are we?​

Why join us?​

Dalriada is a company built by Canadian scientists passionate about finding better, more efficient ways to discover and develop small molecule therapies. As a global leader in medicinal chemistry, bioanalytical chemistry, biology, computational chemistry, proteomics and intellectual property, we strive to be our clients’ ultimate partner.

Be at the forefront with Ontario’s largest and one of Canada’s fastest-growing drug discovery organizations. Our team of passionate and skilled drug discovery scientists is a key factor in Dalriada’s rapid success. Since inception, the company has prioritized creating an environment that promotes professional, scientific, and personal growth and fosters agile innovation through integrative and interdisciplinary learning across all key drug discovery disciplines. We pride ourselves on providing individuals a unique opportunity in small molecule R&D in Ontario.

Who are we?​

Dalriada is a company built by Canadian scientists passionate about finding better, more efficient ways to discover and develop small molecule therapies. As a global leader in medicinal chemistry, bioanalytical chemistry, biology, computational chemistry, proteomics and intellectual property, we strive to be our clients’ ultimate partner.

Why join us?​

Be at the forefront with Ontario’s largest and one of Canada’s fastest-growing drug discovery organizations. Our team of passionate and skilled drug discovery scientists is a key factor in Dalriada’s rapid success. Since inception, the company has prioritized creating an environment that promotes professional, scientific, and personal growth and fosters agile innovation through integrative and interdisciplinary learning across all key drug discovery disciplines. We pride ourselves on providing individuals a unique opportunity in small molecule R&D in Ontario.

The Dalriada Experience

Make a difference

Directly impact and contribute intellectually to the creation of better medicines. Our scientists design and evaluate new drug molecules across multiple therapeutic areas and are named inventors or direct contributors on patents.

Do cutting-edge science, collaboratively

Actively conduct and accomplish advanced science in a state-of-the-art R&D facility. Collaborate with Dalriada’s expert interdisciplinary drug discovery scientists in medicinal & computational chemistry, cell & molecular biology, biophysics & biochemistry, ADME and proteomics (>70% PhD).

Gain global experience

Interact with management teams of innovative clinical-stage pharmaceutical and VC-backed biotech companies from across Canada, US and Europe.

Work with leading experts

Work closely with Dalriada senior leadership and executive team of expert drug discovery scientists, innovators, global pharmaceutical industry executives and entrepreneurs, who collectively have > 145 patents, pharma transactions > $2B, 6 companies founded, >300 years of drug discovery experience, led > 100 drug discovery programs and brought drugs to the clinic and market.

Learn, everyday

Be part of a fast-paced, stimulating, values-based company committed to driving growth, delivering solutions, being accountable and creative.

The Dalriada Experience

Make a difference

Directly impact and contribute intellectually to the creation of better medicines. Our scientists design and evaluate new drug molecules across multiple therapeutic areas and are named inventors or direct contributors on patents.

Do cutting-edge science, collaboratively

Actively conduct and accomplish advanced science in a state-of-the-art R&D facility. Collaborate with Dalriada’s expert interdisciplinary drug discovery scientists in medicinal & computational chemistry, cell & molecular biology, biophysics & biochemistry, ADME and proteomics (>70% PhD).

Gain global experience

Interact with management teams of innovative clinical-stage pharmaceutical and VC-backed biotech companies from across Canada, US and Europe.

Work with leading experts

Work closely with Dalriada senior leadership and executive team of expert drug discovery scientists, innovators, global pharmaceutical industry executives and entrepreneurs, who collectively have > 145 patents, pharma transactions > $2B, 6 companies founded, >300 years of drug discovery experience, led > 100 drug discovery programs and brought drugs to the clinic and market.

Learn, everyday

Be part of a fast-paced, stimulating, values-based company committed to driving growth, delivering solutions, being accountable and creative.

Hear from our employees

Get a glimpse of what it’s like working at Dalriada.

Yasir

“Simply put, Dalriada is a breath of fresh air. In the recently emerging biotech-space of Toronto, it provides talented scientists center stage within an agile, expansive, and responsible approach to drug discovery”

Hardik

“Five Elements: Magnificent work culture, Interdisciplinary learning exposure, Approachable personalities, Team of proficient scientists, Opportunities for advancement, makes Dalriada the best place to work.”

Filip

“Friendly team-members and supportive management fosters an innovative and highly driven work culture where drug discoveries are made.”




Uzma

“What I like the best about working here is the quality of work environment and enthusiastic dedication of everyone in projects to find the answer to the unknown in drug discovery.”



Growing together

Professionally, scientifically, and personally

Growing together

Professionally, scientifically, and personally

The team you'll be working with

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Open Positions

Is one of these a perfect match for who you are and what you do?

Associate Scientist, Mass Spectrometry

Position:                             Associate Scientist, Mass Spectrometry

Reporting to:                    Manager, Proteomics

Employment term:        Full-time

Start date:                         Immediate

Location:                            Mississauga, ON

 

About Dalriada Drug Discovery Inc.:

Founded in 2017, Dalriada is a leading Canadian drug discovery organization specialized in small molecule therapies. Purposely built as an agile, co-located and uniquely integrated drug discovery partner, Dalriada accelerates the discovery and development journey of high value new small molecule therapeutics from concept to IND.

 

Our unique Turn-Key™ operational model offers the global biotechnology industry a full suite of drug discovery, preclinical development, intellectual property, and business expertise to manage and execute tailored R&D programs. To date Dalriada has supported integrated programs of public and venture capital-backed biotech companies, including Antibe, Janpix, Canopy Growth, Oxford Cannabinoid Technologies, atai Life Sciences, and Dunad Therapeutics.

 

Why join? 

Our team of passionate and skilled drug discovery scientists is a key factor in Dalriada’s rapid success.  Since inception, the company has prioritized creating an environment that promotes professional, scientific, and personal growth and fosters agile innovation through integrative and interdisciplinary learning across all key drug discovery disciplines.  We pride ourselves on providing individuals a unique opportunity in small molecule R&D in Ontario to:

  • Make the most direct impact and contribute intellectually to the creation of better medicines. Our scientists design and evaluate new drug molecules across multiple therapeutic areas and are named inventors or direct contributors on patents.
  • Directly interact with management teams of innovative clinical-stage pharmaceutical and VC-backed biotech companies from across Canada, US and Europe.
  • Actively conduct and advance cutting-edge science in a state-of-the-art R&D facility.
  • Collaborate with Dalriada’s expert interdisciplinary drug discovery scientists in medicinal & computational chemistry, cell & molecular biology, biophysics & biochemistry, ADME and proteomics (>70% PhD).
  • Work closely with Dalriada senior leadership and executive team of expert drug discovery scientists, innovators, global pharmaceutical industry executives and entrepreneurs, who collectively have > 145 patents, pharma transactions > $2B, 6 companies founded, >215 years of drug discovery experience, led > 100 drug discovery programs and brought drugs to the clinic and market. 
  • Be at the forefront with Ontario’s largest and one of Canada’s fastest-growing drug discovery organizations. In 2022, the company is on track to grow by 50 per cent to approximately 100 employees.
  • Learn new things every day in a fast-paced, stimulating, values-based company committed to driving growth, delivering solutions, being accountable and creative.

 

Job Summary

The Associate Scientist, Mass Spectrometry will conduct and manage experiments, analyze, and interpret data, and communicate findings under the guidance of senior scientists. They will work collaboratively with teams and troubleshoot technical issues. The ideal candidate has a BSc. or MSc. in Analytical Chemistry, Biochemistry, or Cell Biology, and hands-on lab experience.

 

Specific Duties & Responsibilities

  • Provide support for Mass Spectrometry-based assays to facilitate compound screening, protein target identification, mechanism of action elucidation, and medicinal chemistry efforts.
  • Operate and ensure the proper maintenance of high-resolution mass spectrometers (Orbitrap and TOF) and LC instruments.
  • Collaborate with senior scientists to plan and design mass spectrometry methods for the structural characterization of intact and digested proteins, as well as proteomics experiments.
  • Analyze and interpret experimental results, identifying trends, patterns, and performing statistical analysis.
  • Thoroughly document research workflows, data, and protocols in a meticulous manner.
  • Maintain comprehensive lab notebooks and record experimental results in the designated database.
  • Prepare concise data summaries and reports to effectively communicate project status to diverse audiences, including project teams and executive boards.

 

Education & Certifications

  • BSc or MSc in Analytical Chemistry, Biochemistry, Chemical Biology, or related discipline.

 

Requirements

  • Demonstrated proficiency in a wide range of laboratory techniques commonly used in biochemistry research, including but not limited to protein analysis and quantification, chromatography, spectroscopy, and cell culture.
  • Prior research experience in a related field, substantiated through internships, research projects, or published work.
  • Extensive experience in handling and manipulating biological samples, with a particular focus on proteins and cells.
  • Thorough familiarity with techniques specific to protein analysis, such as intact mass analysis, peptide mapping, and protein characterization.
  • Knowledge and experience in any of the following areas would be highly desirable: protein characterization, proteomics, LC-MS.
  • Proficiency in relevant programs for data analysis and visualization, such as GraphPad Prism, Microsoft Excel, Microsoft PowerPoint, and Microsoft Word.
  • Ability to analyze, interpret, and effectively present scientific data, and develop strategies for experimental design and project advancement.
  • Demonstrates a commitment to scientific excellence while considering cost and process efficiency.
  • Consistently delivers timely results by applying sound judgment and scientific knowledge.
  • Exhibits strong critical thinking skills and generates innovative solutions to challenging scientific inquiries.
  • Approaches work with an entrepreneurial mindset, working independently while seeking professional input when necessary.
  • Possesses exceptional written and verbal communication skills, as well as strong interpersonal abilities.
  • Quick learner, adaptable, and innovative, with a proven ability to collaborate effectively within cross-functional teams.
  • Capable of managing multiple projects simultaneously and meeting aggressive project timelines.

 

This position is open to applicants legally authorized to work in Canada.

 

Dalriada Drug Discovery Inc. is an equal opportunity employer, and we are committed to achieving accessibility by providing accommodation for people with disabilities during our hiring process.

 

Accommodation is available on request for qualified candidates during the recruitment process.

 

All employment is conditional upon completing and obtaining a satisfactory background check which may include educational and employment verification, business references and a criminal record investigation.

 

Apply Here!

Lab Technician, compound management

Position:                             Lab Technician, compound management

Reporting to:                    Director, Biology and Biophysics

Employment term:        Permanent Full-time

Start date:                         Immediate

Location:                            Mississauga, ON

 

About Dalriada Drug Discovery Inc.:

Founded in 2017, Dalriada is a leading Canadian drug discovery organization specialized in small molecule therapies. Purposely built as an agile, co-located and uniquely integrated drug discovery partner, Dalriada accelerates the discovery and development journey of high value new small molecule therapeutics from concept to IND.

 

Our unique Turn-Key™ operational model offers the global biotechnology industry a full suite of drug discovery, preclinical development, intellectual property, and business expertise to manage and execute tailored R&D programs. To date Dalriada has supported integrated programs of public and venture capital-backed biotech companies, including Antibe, Janpix, Canopy Growth, Oxford Cannabinoid Technologies, atai Life Sciences, and Dunad Therapeutics.

 

Why join? 

Our team of passionate and skilled drug discovery scientists is a key factor in Dalriada’s rapid success.  Since inception, the company has prioritized creating an environment that promotes professional, scientific, and personal growth and fosters agile innovation through integrative and interdisciplinary learning across all key drug discovery disciplines.  We pride ourselves on providing individuals a unique opportunity in small molecule R&D in Ontario to:

  • Make the most direct impact and contribute intellectually to the creation of better medicines. Our scientists design and evaluate new drug molecules across multiple therapeutic areas and are named inventors or direct contributors on patents.
  • Directly interact with management teams of innovative clinical-stage pharmaceutical and VC-backed biotech companies from across Canada, US and Europe.
  • Actively conduct and advance cutting-edge science in a state-of-the-art R&D facility.
  • Collaborate with Dalriada’s expert interdisciplinary drug discovery scientists in medicinal & computational chemistry, cell & molecular biology, biophysics & biochemistry, ADME and proteomics (>70% PhD).
  • Work closely with Dalriada senior leadership and executive team of expert drug discovery scientists, innovators, global pharmaceutical industry executives and entrepreneurs, who collectively have > 145 patents, pharma transactions > $2B, 6 companies founded, >215 years of drug discovery experience, led > 100 drug discovery programs and brought drugs to the clinic and market. 
  • Be at the forefront with Ontario’s largest and one of Canada’s fastest-growing drug discovery organizations. In 2022, the company is on track to grow by 50 per cent to approximately 100 employees.
  • Learn new things every day in a fast-paced, stimulating, values-based company committed to driving growth, delivering solutions, being accountable and creative.

 

Job Summary

Dalriada is seeking an enthusiastic individual to join our team in Mississauga, as a Lab Technician, compound management. This position will play a critical role in our research and development efforts by overseeing the organization, management, and maintenance of the compounds and compound libraries. The successful candidate will be responsible for handling, tracking and inventory management of a diverse range of chemical compounds and ensuring their availability for ongoing projects. The selected candidate will collaborate with various internal teams, including medicinal chemists, biologists, and project managers, to ensure efficient compound logistics and timely delivery. This position requires a strong attention to detail, excellent organizational skills, and the ability to work effectively in a fast-paced and collaborative environment.

 

Specific Duties & Responsibilities

  • Track, receive, register, and store research samples, reagents, and solvents.
  • Organize and track compound shipments domestically and internationally.
  • Prepare research samples (weigh the solids, dissolve, dilute and transfer the solutions) including preparation of aliquots and daughter plates.
  • Manage and maintain chemical inventory/compound database.
  • Perform laboratory manager duties, such as ordering consumables, organizing labware items, performing basic laboratory instrumentation maintenance, and scheduling chemical waste pick-up, adhering to health and safety (EHS) requirements.

 

Education & Certifications

  • A college certificate or bachelor’s degree in chemistry, biochemistry, or a related field.

 

Requirements

  • A minimum of 2 years of relevant experience in compound management within a biotech, pharmaceutical, or CRO setting is highly preferred.
  • Strong knowledge of compound handling, storage, and tracking best practices.
  • Familiarity with compound databases and inventory management systems.
  • Proficient in using laboratory equipment and software relevant to compound management such as analytical balance, micropipette, well-plates etc.
  • Understanding of chemical safety regulations and experience working in a lab environment.
  • Excellent organizational and time management skills, with the ability to prioritize tasks effectively.
  • Strong attention to detail and accuracy, ensuring the integrity of compound data and inventory.
  • Collaborative mindset and ability to work effectively within a multidisciplinary team.
  • Effective communication skills, both written and verbal.
  • Ability to adapt to changing priorities and work well in a fast-paced, dynamic environment.

 

This position is open to applicants legally authorized to work in Canada.

 

Dalriada Drug Discovery Inc. is an equal opportunity employer, and we are committed to achieving accessibility by providing accommodation for people with disabilities during our hiring process.

 

Accommodation is available on request for qualified candidates during the recruitment process.

 

All employment is conditional upon completing and obtaining a satisfactory background check which may include educational and employment verification, business references and a criminal record investigation.

 

Apply Here!

Scientist, Mass Spectrometry

Position:                      Scientist, Mass Spectrometry

Reporting to:             Manager, Proteomics

Employment term:  Permanent Full-time

Start date:                   Immediate

Location:                     Mississauga, ON

 

About Dalriada Drug Discovery Inc.:

Founded in 2017, Dalriada is a leading Canadian drug discovery organization specialized in small molecule therapies. Purposely built as an agile, co-located and uniquely integrated drug discovery partner, Dalriada accelerates the discovery and development journey of high value new small molecule therapeutics from concept to IND.

 

Our unique Turn-Key™ operational model offers the global biotechnology industry a full suite of drug discovery, preclinical development, intellectual property, and business expertise to manage and execute tailored R&D programs. To date Dalriada has supported integrated programs of public and venture capital-backed biotech companies, including Antibe, Janpix, Canopy Growth and Dunad Therapeutics.

 

Why join? 

Our team of passionate and skilled drug discovery scientists is a key factor in Dalriada’s rapid success.  Since inception, the company has prioritized creating an environment that promotes professional, scientific, and personal growth and fosters agile innovation through integrative and interdisciplinary learning across all key drug discovery disciplines.  We pride ourselves on providing individuals a unique opportunity in small molecule R&D in Ontario to:

  • Make the most direct impact and contribute intellectually to the creation of better medicines. Our scientists design and evaluate new drug molecules across multiple therapeutic areas and are named inventors or direct contributors on patents.
  • Directly interact with management teams of innovative clinical-stage pharmaceutical and VC-backed biotech companies from across Canada, US and Europe.
  • Actively conduct and advance cutting-edge science in a state-of-the-art R&D facility.
  • Collaborate with Dalriada’s expert interdisciplinary drug discovery scientists in medicinal & computational chemistry, cell & molecular biology, biophysics & biochemistry, ADME and proteomics (>70% PhD).
  • Work closely with Dalriada senior leadership and executive team of expert drug discovery scientists, innovators, global pharmaceutical industry executives and entrepreneurs, who collectively have > 145 patents, pharma transactions > $2B, 6 companies founded, >215 years of drug discovery experience, led > 100 drug discovery programs and brought drugs to the clinic and market. 
  • Be at the forefront with Ontario’s largest and one of Canada’s fastest-growing drug discovery organizations. In 2022, the company is on track to grow by 50 per cent to approximately 100 employees.
  • Learn new things every day in a fast-paced, stimulating, values-based company committed to driving growth, delivering solutions, being accountable and creative.

 

Job Summary

The Proteomics Scientist will conduct and manage experiments, analyze, and interpret data, and communicate findings. They will work collaboratively with teams, troubleshoot technical issues, and guide junior team members. The ideal candidate has a Ph.D. in Biochemistry or Analytical Chemistry, demonstrated proteomics expertise, and experience with sample preparation, LC-MS/MS, and data analysis. Strong analytical skills, project management, and teamwork are required, as well as excellent communication and presentation skills.

 

Specific Duties & Responsibilities

  • Provide mass spectrometry expertise to support Dalriada’s drug discovery programs.
  • Execute MS-based assays to facilitate compound screening, identify protein targets, elucidate mechanism of action, and support medicinal chemistry efforts.
  • Use, maintain, and troubleshoot high-resolution mass spectrometers (Orbitrap and TOF), and LC instruments.
  • Develop and conduct mass spectrometry methods for structural characterization of intact and digested proteins.
  • Design and conduct proteomic experiments (including experimental design, data collection, interpretation, and presentation).
  • Troubleshoot and develop technical solutions to optimize experiments for robust data output.
  • Train and supervise junior team members.
  • Monitor, review, and critically interpret published research to support experimental efforts.
  • Carefully document research workflows, data, and protocols.
  • Maintain lab notebooks and document the experimental results in database.
  • Prepare data summaries and reports to communicate project status among diverse audiences such as project teams and executive boards.

 

Education & Certifications

  • PhD or MSc in Analytical Chemistry, Biochemistry, Chemical Biology, or related discipline.
  • Post-graduate lab experience in drug discovery settings is desirable but not necessary.

 

Requirements

  • Deep knowledge and demonstrated history in MS-based analysis and quantification.
  • Experience in the operation and maintenance of HRMS and LC instruments.
  • Experience in intact mass protein analysis and peptide mapping analysis.
  • Experience with any of the following is a definite asset: protein characterization, proteomics, TOF-MS, ADME assays.
  • Experience with related software such as MassHunter, BioConfirm, Skyline, PEAKS, Proteome Discoverer, etc.) is desired.
  • Proficient in relevant programs for data analysis and visualization, e.g., GraphPad Prism, Microsoft Excel, Microsoft PowerPoint, Microsoft Word.
  • Ability to analyze, interpret, and present scientific data, and propose next steps in experimental design and project strategy.
  • Driven by scientific excellence and cost/process efficiency.
  • Offers timely results through sound judgment and scientific knowledge.
  • Thinks critically and generates creative solutions to challenging scientific questions.
  • Approaches work with an entrepreneurial mindset, working independently and seeking professional input when necessary.
  • Superior communication skills (written and verbal) and interpersonal skills.
  • Fast learner, flexible, and innovative, able to work collaboratively within cross-functional teams.
  • Able to manage multiple projects simultaneously and meet aggressive project timelines.

 

This position is open to applicants legally authorized to work in Canada.

 

Dalriada Drug Discovery Inc. is an equal opportunity employer, and we are committed to achieving accessibility by providing accommodation for people with disabilities during our hiring process.

Accommodation is available on request for qualified candidates during the recruitment process.

All employment is conditional upon completing and obtaining a satisfactory background check which may include educational and employment verification, business references and a criminal record investigation.

 

Apply Here!

Scientist Synthetic / Medicinal Chemistry

Position:                                  Scientist Synthetic / Medicinal Chemistry

Reporting to:                         Manager, Medicinal Chemistry

Employment term:              Permanent Full-time

Start date:                            Immediate

Location:                                 Mississauga, ON

 

About Dalriada Drug Discovery Inc.:

Founded in 2017, Dalriada is a leading Canadian drug discovery organization specialized in small molecule therapies. Purposely built as an agile, co-located and uniquely integrated drug discovery partner, Dalriada accelerates the discovery and development journey of high value new small molecule therapeutics from concept to IND.

 

Our unique Turn-Key™ operational model offers the global biotechnology industry a full suite of drug discovery, preclinical development, intellectual property, and business expertise to manage and execute tailored R&D programs. To date Dalriada has supported integrated programs of public and venture capital-backed biotech companies, including Antibe, Janpix, Canopy Growth, Oxford Cannabinoid Technologies, atai Life Sciences, and Dunad Therapeutics.

 

Why join? 

Our team of passionate and skilled drug discovery scientists is a key factor in Dalriada’s rapid success.  Since inception, the company has prioritized creating an environment that promotes professional, scientific, and personal growth and fosters agile innovation through integrative and interdisciplinary learning across all key drug discovery disciplines.  We pride ourselves on providing individuals a unique opportunity in small molecule R&D in Ontario to:

  • Make the most direct impact and contribute intellectually to the creation of better medicines. Our scientists design and evaluate new drug molecules across multiple therapeutic areas and are named inventors or direct contributors on patents.
  • Directly interact with management teams of innovative clinical-stage pharmaceutical and VC-backed biotech companies from across Canada, US and Europe.
  • Actively conduct and advance cutting-edge science in a state-of-the-art R&D facility.
  • Collaborate with Dalriada’s expert interdisciplinary drug discovery scientists in medicinal & computational chemistry, cell & molecular biology, biophysics & biochemistry, ADME and proteomics (>70% PhD).
  • Work closely with Dalriada senior leadership and executive team of expert drug discovery scientists, innovators, global pharmaceutical industry executives and entrepreneurs, who collectively have > 145 patents, pharma transactions > $2B, 6 companies founded, >215 years of drug discovery experience, led > 100 drug discovery programs and brought drugs to the clinic and market. 
  • Be at the forefront with Ontario’s largest and one of Canada’s fastest-growing drug discovery organizations.
  • Learn new things every day in a fast-paced, stimulating, values-based company committed to driving growth, delivering solutions, being accountable and creative.

 

Job Summary

As a Scientist you will apply your knowledge of organic and medicinal chemistry for the synthesis of new compounds destined for a variety of drug discovery programs and screening platforms. The position requires performing multi-step syntheses of novel small molecules and preparing libraries of compounds that will be tested and characterized either internally or by our collaborators/clients. The successful candidate will join a vibrant and multi-disciplinary drug discovery team comprised of talented research individuals spanning a variety of disciplines.

 

Specific Duties & Responsibilities

  • Execute synthesis of novel small molecule modulators of various biological targets. Purify and characterize synthetic compounds as well.
  • Maintain accurate and up-to-date laboratory notebooks which fully comply with all company policies.
  • Ensure compliance with all regulatory and safety governmental and institutional requirements.
  • The candidate may also be required to perform other duties within the team including but not limited to:
    • procure and maintain inventories of reagents, laboratory consumables or other samples
    • operate and maintain laboratory instruments
    • ensure well organized experimental and regulatory documentation
    • report and summarize experimental details to supervisor
    • maintain the organization and cleanliness of the laboratory space

 

Education & Certifications

  • Minimum M.Sc. in synthetic organic chemistry
  • Preference will be given to candidates with previous experience in synthetic organic/ medicinal chemistry setting

 

Knowledge, Experience & Technical Skills

  • Two-years’ experience in synthetic organic and/or medicinal chemistry (including graduate work) with expertise in small molecule synthesis, purification and analytical characterization by NMR (carbon, proton, fluorine), MS, HPLC, IR, TLC, LC-MS is required.
  • Thinks critically and generates creative solutions to challenging scientific questions.
  • Approaches work with an entrepreneurial mindset, working independently and seeking professional input when necessary.
  • Superior communication skills (written and verbal) and interpersonal skills.
  • Fast learner, flexible, and innovative, able to work collaboratively within cross-functional teams.
  • Able to manage multiple projects simultaneously and meet aggressive project timelines.

 

This position is open to applicants legally authorized to work in Canada.

 

Dalriada Drug Discovery Inc. is an equal opportunity employer, and we are committed to achieving accessibility by providing accommodation for people with disabilities during our hiring process. Accommodation is available on request for qualified candidates during the recruitment process.

 

All employment is conditional upon completing and obtaining a satisfactory background check which may include educational and employment verification, business references and a criminal record investigation.

 

Apply Here!

Scientist/Senior Scientist, Biology

Position:                             Scientist/Senior Scientist, Biology

Reporting to:                    Director, Biology and Biophysics

Employment term:        Permanent Full-time

Start date:                         Immediate

Location:                            Mississauga, ON

 

About Dalriada Drug Discovery Inc.:

Founded in 2017, Dalriada is a leading Canadian drug discovery organization specialized in small molecule therapies. Purposely built as an agile, co-located and uniquely integrated drug discovery partner, Dalriada accelerates the discovery and development journey of high value new small molecule therapeutics from concept to IND.

 

Our unique Turn-Key™ operational model offers the global biotechnology industry a full suite of drug discovery, preclinical development, intellectual property, and business expertise to manage and execute tailored R&D programs. To date Dalriada has supported integrated programs of public and venture capital-backed biotech companies, including Antibe, Janpix, Canopy Growth, Oxford Cannabinoid Technologies, atai Life Sciences, and Dunad Therapeutics.

 

Why join? 

Our team of passionate and skilled drug discovery scientists is a key factor in Dalriada’s rapid success.  Since inception, the company has prioritized creating an environment that promotes professional, scientific, and personal growth and fosters agile innovation through integrative and interdisciplinary learning across all key drug discovery disciplines.  We pride ourselves on providing individuals a unique opportunity in small molecule R&D in Ontario to:

  • Make the most direct impact and contribute intellectually to the creation of better medicines. Our scientists design and evaluate new drug molecules across multiple therapeutic areas and are named inventors or direct contributors on patents.
  • Directly interact with management teams of innovative clinical-stage pharmaceutical and VC-backed biotech companies from across Canada, US and Europe.
  • Actively conduct and advance cutting-edge science in a state-of-the-art R&D facility.
  • Collaborate with Dalriada’s expert interdisciplinary drug discovery scientists in medicinal & computational chemistry, cell & molecular biology, biophysics & biochemistry, ADME and proteomics (>70% PhD).
  • Work closely with Dalriada senior leadership and executive team of expert drug discovery scientists, innovators, global pharmaceutical industry executives and entrepreneurs, who collectively have > 145 patents, pharma transactions > $2B, 6 companies founded, >215 years of drug discovery experience, led > 100 drug discovery programs and brought drugs to the clinic and market. 
  • Be at the forefront with Ontario’s largest and one of Canada’s fastest-growing drug discovery organizations. In 2022, the company is on track to grow by 50 per cent to approximately 100 employees.
  • Learn new things every day in a fast-paced, stimulating, values-based company committed to driving growth, delivering solutions, being accountable and creative.

 

Job Summary

We are looking for a motivated cell biologist to join our research team. The successful candidate will be responsible for designing and optimizing high-quality cell-based and functional assays for various pharmacological target classes. In addition, the candidate will conduct validation of the assays for screening of small molecules synthesized during hit-lead and lead optimization stages and execute routine cell-based screening assays to ensure rapid and high-quality data delivery. The candidate will also troubleshoot and develop technical solutions to optimize experiments to deliver robust data output.

 

Specific Duties & Responsibilities

  • Design and optimize high-quality cell-based and functional assays for various targets, including (but not limited to) GPCRs, nuclear receptors, ion channels, kinases, transcription factors, immunology, inflammation, oncology
  • Conduct validation of the assays for screening of small molecules synthesized during hit-lead and lead optimization stages
  • Execute routine cell-based screening assays to ensure rapid and high-quality data delivery
  • Troubleshoot and develop technical solutions to optimize experiments to deliver robust data output
  • Collaborate closely with chemists and biochemists to characterize small molecule mechanism of action (MoA) and advance lead optimization
  • Organize, track, and advance projects in a timely fashion
  • Maintain lab notebooks and document experimental results within a database
  • Carefully document research workflows, data, and protocols
  • Prepare data summaries and reports to communicate project status to diverse audiences such as project teams and executive boards
  • Monitor, review, and critically interpret published research to support experimental efforts
  • Train and supervise junior team members

 

Education & Certifications

  • MSc/PhD in cell biology, pharmacology, virology or related discipline with relevant associated publications
  • Experience in a drug discovery setting preferred.

 

Requirements

  • Deep knowledge and experience with mammalian cell culture and aseptic techniques is a must
  • Practical experience of a wide range of luminescence- and fluorescence-based cell biology assays in 96- and 384-well plate formats
  • Hands-on experience in validation, optimization and execution of cellular assays applying multiple techniques for DNA, RNA, and protein analysis
  • Strong background in signal transduction and pharmacology of GPCRs is a plus
  • Ability to conceive, design, and execute hypothesis-testing experiments that directly contribute to project success
  • Proficient in relevant programs for data analysis and visualization, e.g., GraphPad Prism, Microsoft Excel, Microsoft PowerPoint, Microsoft Word. Experience in bioinformatics is a plus.
  • Ability to analyze, interpret, and present scientific data, and propose next steps in both experimental and project design and overall strategy
  • Ability to plan, organize, manage, and direct a complex variety of project activities to deliver the required business benefit
  • Ability to make timely decisions through the use of sound judgement and technical knowledge
  • Critical thinking skills and the ability to generate creative solutions to challenging scientific questions
  • An entrepreneurial mindset, with the ability to work independently and identify when to reach out for professional input
  • Superior communication and interpersonal skills, with the proven ability to effectively communicate with all levels of the organization
  • Ability to explain controversial or complex issues to key leadership
  • Fast learner, flexible, innovative with the ability to work effectively in highly cross-functional teams
  • Ability to handle multiple projects simultaneously and meet aggressive project timelines

 

This position is open to applicants legally authorized to work in Canada.

 

Dalriada Drug Discovery Inc. is an equal opportunity employer, and we are committed to achieving accessibility by providing accommodation for people with disabilities during our hiring process.

 

Accommodation is available on request for qualified candidates during the recruitment process.

 

All employment is conditional upon completing and obtaining a satisfactory background check which may include educational and employment verification, business references and a criminal record investigation.

 

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Adam Davenport, PhD

Chief R&D Officer

Adam is Dalriada’s Chief R&D Officer. A seasoned drug hunter and innovator, he brings over 22 years of hands-on life science and partnership organization experience, having contributed to drug candidates and clinical assets through both governance and leadership roles.

Prior to Dalriada, Adam’s outstanding career was spent at Evotec, then Oxford Asymmetry International, which he joined in 2001. There, he gained extensive experience from Hit ID through to IND, across diverse modalities, target classes (GPCRs, ion-channels, PPIs, CNS, kinases, enzymes) and therapeutic areas (pain, inflammation, cognition, metabolic, Women’s Health and respiratory).

As a Project Leader, Adam has progressed multiple projects through Discovery into Clinical evaluation and is lead inventor of P2X3R antagonists Eliapixant and Filopixant, achieving Phase 2a PoCs in Persistent Chronic Cough (PCC), and Bradykinin B1R antagonist Fulimetibant, undergoing a Phase 2a study to treat diabetic neuropathic pain (DNP).

Adam’s promotion to VP Medicinal Chemistry saw him take on scientific and strategic portfolio responsibilities as well as operational duties in Abingdon, UK. Progression through Senior to Executive VP expanded Adam’s leadership and strategic influence on the organisation, where he established and led as Head of Global Molecular Discovery, a multi-modality data-driven Design and Synthesis function based in the UK, FR, IT and US.

Passionate about science and communication, Adam has authored over 55 patents, publications and external presentations and was co-recipient of the Bayer Healthcare Drug Discovery Award for Collaborative Innovation in 2017.

Adam holds a B.Sc. Honours degree in Chemistry and a PhD in Organometallic Chemistry from the University of Leicester, UK.

Frosty Loechel, PhD

SVP Biology

Frosty is Dalriada’s Head of Biology, responsible for the scientific strategy of the discovery program in biology and a key contributor to the continuous evaluation of our scientific capabilities, operations, and infrastructure. He brings 20 years’ academic experience and 25 years working in pharma, biotech, and CROs.

Before joining Dalriada, Frosty gained exceptional experience in discovery programs at Evotec. First as a VP, Metabolic diseases, he built up a large department running iPSC work, in vitro pharmacology, advanced cellular platforms, transcriptomics, imaging, and data science. Then, as SVP, Therapeutic Area Lead and Scientific Director, he led on new collaborative drug discovery agreements with pharma/biotech partners and on the strategy of project portfolio in major multi-target collaborations.

Prior experience includes work at Zealand Pharma, where he focused on peptide drugs for a portfolio of diabetes and obesity projects. His earlier career was spent at Lundbeck, Thermo Fisher, Neurosearch and BioImage, where he gained a strong background in a broad spectrum of scientific areas.

Frosty has been involved in hundreds of drug discovery projects and gained a wealth of experience across multiple areas and therapeutic modalities including CNS and metabolic diseases. His expertise spans all stages of drug discovery, from target identification and validation to Hit-to-Lead and Lead Optimization, and nomination of preclinical candidates. He is familiar with multiple modalities, from small molecules, to peptides, to biologics, and brings extensive experience with target classes such as GPCRs, kinases, transporters, ion channels and proteases.

Frosty has a B.A. in Biochemistry from the University of Kansas, and a Ph.D. from the Faculty of Health Sciences of the University of Copenhagen. He is a Danish citizen and is fluent in English, Danish, and Italian.

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Brian Sequeira

Brian Sequeira

Director, Information Systems, PMO

As Director of Information Systems and PMO, Brian leads the IT, PMO and Procurement functions. With a strong foundation in technology, a successful track record in leading cross functional and multi-disciplinary project management teams, and in-depth experience in purchasing and materials management, Brian is passionate about delivering to and exceeding client expectations through critical thinking, analysis and effective communication. He brings more than 20 years experience in various industries including corporate law, pharmaceuticals, biopharmaceuticals and big data market research.

Brian completed his BSc degree in Computer Science from the University of Toronto and certified as a Project Management trainer with Kepner Tregoe.

Lisa Cline

Lisa Cline

Director, Human Resources​

As the Director of Human Resources (HR), Lisa leads this function at Dalriada. Lisa is recognized as a pragmatic partner, team builder and innovator who brings balance and clarity to HR policies, practices, and procedures.

With more than 25 years in a management capacity, Lisa is known for designing and developing programs, performance improvement measures and policies that help organizations build highly engaged workplaces, boost their bottom line, and defuse workplace issues before they escalate.

She began her HR career at GlaxoSmithKline advancing through increasingly responsible positions and supporting practically every division within the company. Lisa has also operated her own HR consultancy. Since joining Dalriada in 2020, Lisa has established an efficient and engaging HR infrastructure that delivers sustainable organizational and cultural success.

Lisa attained her Certified Human Resources Leader designation, (CHRL) from the University of Toronto.

Eric Chow

Eric Chow

Director, Finance

As Director of Finance, Eric leads Dalriada’s finance function. He brings more than 20 years’ experience leading finance departments for multinational and private service-based companies.

Over his career, Eric has worked internationally in the US and the UK. Eric completed his BComm Finance and BA Economics from the University of Calgary and is a CPA, CMA.

Kamran Syed

Kamran Syed

Vice President Business Development, North America

As Vice President Business Development, North America Kamran overseas all client acquisitions for this market. Known for his transformative leadership style, Kamran is focused on forging strategic partnerships between Dalriada and BioPharma companies to advance concept to IND drug discovery and development efforts.

Over the past twenty years, Kamran has driven the identification of commercial opportunities and created sophisticated integrated discovery collaborations for clients. He has worked for a myriad of leading Life Science and Diagnostic organizations including Abbot Laboratories, ThermoFisher Scientific, Cepheid, Novartis, and Illumina. He has also consulted with molecular diagnostics and genomics start-ups to provide strategic market development and commercialization services.

Kamran holds a BSc in Biology from Loyola University and an MBA from the University of Phoenix.

Harpreet Kaur

Harpreet Kaur, PhD

Director Chemistry & ADME

As Director of R&D Operations, Harpreet leads Dalriada’s Chemistry and ADME functions. Passionate about building highly effective, result-oriented teams, Harpreet is known for her strong rapport with clients and inter-disciplinary colleagues.

Harpreet brings more than 20 years R&D experience in both academic and industry settings. Beginning her career at Dalton Pharma Services as a medicinal chemist, Harpreet has progressed into roles such as chemistry team leader, chemistry manager and associate director for R&D operations. Harpreet brings a broad range of drug development experience in preclinical, clinical, and commercial stages for more than 10 pre-clinical candidates and 2 commercial products. Her experience also includes contract research, process development and analytical method development and validation. She has served as SME for process development and analytical method development during FDA and Health Canada audits.

Harpreet completed her BSc degree in Biological Sciences, MSc and PhD degree in Organic Chemistry from Kurukshetra University, India.

Mohammad Eram

Mohammad Eram, PhD

Director Biology & Biophysics

Mohammad attained his PhD in Biochemistry and Enzymology at the University of Waterloo (Canada) and holds MSc degree in Medical Microbiology and a BSc degree in Cell and Molecular Biology. As the Director of Biology Department at Dalriada, he oversees the work of the cell biology, biochemistry and biophysics and proteomics teams.

Prior to joining Dalriada, Mohammad worked on early stage hit discovery projects at the Structural Genomics Consortium in Toronto, including projects in collaboration with Bayer, Takeda, Eli Lilly, and Merck. His work at SGC focused on biochemical and biophysical methods with applications to high-throughput and fragment-based drug discovery.

With over 17 years in biochemical/biophysical assays and small molecule R&D, Mohammad was involved in programs spanning small molecule inhibitor modalities including allosteric inhibitors, tight binders, targeted covalent therapeutics, and protein degraders. These programs covered a diverse range of protein targets including transcription factors, epigenetic modulators, oxidoreductases, dehydrogenases, kinases, methyl- and acetyltransferases, deacetylases, demethylases, PPI, GPCRs, and transcription regulators.

Jeff O’Meara

Jeff O’Meara, MSc

VP Drug Discovery

As Vice President, Drug Discovery at Dalriada, Jeff is responsible for overseeing all drug discovery activities from target identification to pre-clinical development. Jeff has nearly 30 years of drug discovery experience in hit ID, hit to lead, lead optimization and candidate nomination in projects targeting kinases, protein-protein interactions, protein degraders, covalent inhibitors, proteases and GPCRs in the areas of anti-infectives, oncology, immunomodulation, pain and CNS therapeutics. Prior to Dalriada, Jeff was Head of Research at M4K Pharma where he led a successful multinational open science lead optimization drug discovery project targeting DIPG, a rare childhood cancer.

Previously, Jeff spent 8 years as an integral part of the Ontario Institute for Cancer Research’s Drug Discovery team where he drove hit to lead and lead optimization projects of which two were eventually partnered with pharma in deals totaling > $2B. Jeff also trained for 17 years as a medicinal chemist and project team leader at Boehringer Ingelheim Canada Ltd. where he helped discover several novel antivirals that progressed to clinical trials. He has published more than 50 papers and patents in the fields of medicinal chemistry and drug discovery and in 2010 was the recipient of the American Chemical Society’s TAOC award.

Jeff has an M.Sc. in organic chemistry from University of Ottawa.

Tom Coulter

Tom Coulter, PhD

Head, Drug Discovery Programs and Partnerships

Tom is part of the R&D leadership team, overseeing partnership activities, drug discovery program planning and execution, as well as lifecycle management for current and prospective partners.

Over the past three decades, Tom has held senior roles in European pharma and biotech, including almost 20 years in contract research with Evotec as Senior Vice President, Drug Discovery, and more recently growing and leading Selvita’s integrated drug discovery portfolio.

Tom’s background is in medicinal chemistry, and he has extensive experience in the discovery and delivery of new small molecule and biologic agents targeting enzymes, GPCRs and other cell membrane targets including ion channels and SNARE proteins. He has managed multiple drug discovery programs covering the hit identification, hit to lead, and lead optimization stages of drug discovery, including 15 projects resulting in nomination of preclinical development candidates in the fields of cancer, inflammation, endocrine disease and antivirals. Tom has also contributed to the identification of multiple investigational new drugs. In recent years Tom has driven the identification of commercial opportunities as well as the creation and execution of sophisticated integrated discovery collaborations for clients.

Tom has a BSc (Hons) degree in chemistry from the Queen’s University of Belfast and a PhD in organic chemistry from the University of Leeds under Professor Ron Grigg. After completing his PhD, he joined Jim Thomas’ group at the University of Manchester before starting his industrial career at Organon.

Rav Kumar

Rav Kumar, PhD

Chief Strategy Officer

Dr. Rav Kumar is Chief Strategy Officer at Dalriada. He spent 25 years with GlaxoSmithKline (GSK) in the UK, France and Canada at vice-president level leading pharmaceutical R&D and business development. Key areas of expertise include formulation development, regulatory submissions, manufacturing and GMP audits. He has been involved with development of numerous medicines and vaccines plus many successful business change initiatives.

Most recently, he was Managing Director for Apotex in India (Bangalore and Mumbai), leading over 2,000 professionals in Pharmaceutical R&D, Manufacturing, Quality, Regulatory Affairs & Commercial Services.

Dr. Kumar is passionate about growing Canadian Life Sciences and has been involved with many industry-academic-government collaborations for which he was recognized with the Award for Leadership in in Canadian Pharmaceutical Sciences. He conceived the $150M spinout of GSK’s vaccines R&D to create the Neomed Vaccines and Biologics Centre of Excellence in Montreal. Other contributions include the CIHR Steering Committee for Patient Oriented Research, the Board of CQDM Research Consortium in Quebec and President of the Canadian Society for Pharmaceutical Sciences.

Dr. Kumar also serves as Director of The Centre for Medicinal Chemistry and an Assistant Professor at University of Toronto. He has a Pharmacy Degree and completed a PhD in Novel Drug Delivery at University of Bath in the UK.

Charlie Younger

Charlie Younger, PhD

Chief Operating Officer

Charlie joined Dalriada in 2020 as Chief Operating Officer, bringing over 25 years of pharma/biopharma experience. Charlie has a proven track record of leading organizations through rapid growth and transformations.

Charlie started his career as an Analytical Scientist at Glaxo and has taken on progressive leadership roles in pharma/biopharma. Charlie has worked with leading private and public pharma/biopharma organizations including leadership roles at CROs such as Patheon and Therapure Biopharma. He has also served as COO in both public and private organizations.

Driven by a personal passion to grow R&D in Canada, he has been a contributing member on multiple SR&ED tasks forces and executive roles in training organizations.

More recently, Charlie runs his own professional services business since 2016, helping companies grow and/or streamline operations for start-ups through to $B+ multinationals. He completed an HBSc in Chemistry at Western University (Canada) and a PhD in Organic Chemistry at McMaster University (Canada).

Patrick Gunning

Patrick Gunning, PhD

Co-founder & CSO

Patrick is a Professor of Chemistry at the University of Toronto, Canada Research Chair in Medicinal Chemistry, and Founder and Chief Scientific Director of the Centre for Medicinal Chemistry (UofT). Patrick obtained his PhD at the University of Glasgow in 2005 under the supervision of Profs. Robert Peacock and Andrew C. Benniston, and conducted post-doctoral studies at Yale University with Prof Andrew Hamilton.

Patrick’s research has focused on developing inhibitors of numerous protein classes, including transcription factors, kinases, and epigenetic targets, using novel covalent therapeutics and monovalent protein degraders. Patrick has published ~120 research papers, is a Fellow of the Royal Society of Chemistry, won 20 research awards including Canada’s Top 40 under 40, the 2010 Boehringer Ingelheim Young Investigator Award, the 2012 RSC MedChemComm Emerging Investigator Lectureship by the Royal Society for Chemistry, Rose Winer Levin Lectureship at the Dana-Farber Cancer Institute (2015), and the 2016 Canadian Society for Chemistry’s Bernard Belleau award.

Patrick, the co-founder and CSO of Dalriada Drug Discovery, has founded three other biotech companies with over $34M in funding, including Janpix Inc, now a Centessa Pharmaceuticals’ company, Dunad Therapeutics, and Dalriada Therapeutics.

Diana Kraskouskaya

Diana Kraskouskaya, PhD

Co-founder & CEO

Diana completed Honors BSc Degree in Molecular Biology and PhD in Medicinal Chemistry from the University of Toronto, and is a co-founder of two other biotechs, which have raised > $10 M in VC funding.

During her time in academia and biotech, Diana worked on diverse small molecule programs across protein-protein interactions, epigenetics, GPCRs, covalent inhibitors, and is an inventor on several patents.

As a co-founder and Chief Executive Officer of Dalriada, Diana brings to Dalriada years of leadership and hands-on cross-disciplinary biotech and drug discovery experience spanning areas of company building, scientific & IP program strategy, and operations. ​

Following completion of her PhD, Diana took appointment as a research manager of the Centre for Medicinal Chemistry, where she was involved in multiple drug discovery programs and provided oversight over the build-out of the >$100 M integrated drug discovery infrastructure at the University of Toronto. Diana co-founded and led two other biotechs, Dunad Therapeutics and Dalriada Therapeutics. In this process she recognized the shortcomings of the existing options for outsourcing innovative science, which led to the creation of Dalriada Drug Discovery’s Turn-Key™ Model. With this new model and under Diana’s leadership the company has grown to over 60 people within 3 years. ​

Diana is the recipient of several entrepreneurship awards, including RBC Prize for Innovation & Entrepreneurship and the 2018 MNP Future Leaders awards.

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