{"id":2135,"date":"2022-10-03T13:23:13","date_gmt":"2022-10-03T17:23:13","guid":{"rendered":"https:\/\/dalriadatx.com\/?page_id=2135"},"modified":"2023-01-19T14:36:46","modified_gmt":"2023-01-19T19:36:46","slug":"in-vivo-dmpk","status":"publish","type":"page","link":"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/dmpk\/in-vivo-dmpk\/","title":{"rendered":"In-Vivo DMPK"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"2135\" class=\"elementor elementor-2135\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-top-section elementor-element elementor-element-ec78d19 elementor-section-height-min-height elementor-section-items-stretch elementor-section-content-middle elementor-section-boxed elementor-section-height-default jltma-glass-effect-no\" data-id=\"ec78d19\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-e56faf0 jltma-glass-effect-no\" data-id=\"e56faf0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dc2a77a jltma-glass-effect-no elementor-widget elementor-widget-spacer\" data-id=\"dc2a77a\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 26-03-2024 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container{height:100%;width:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty,.e-con>.elementor-widget-spacer.elementor-widget-empty{position:relative;min-height:22px;min-width:22px}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon,.e-con>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon{position:absolute;top:0;bottom:0;left:0;right:0;margin:auto;padding:0;width:22px;height:22px}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-923d575 jltma-glass-effect-no\" data-id=\"923d575\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d684473 elementor-widget elementor-widget-heading\" data-id=\"d684473\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 26-03-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\">Turn-Key Discovery Labs\u200b<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-top-section elementor-element elementor-element-bab7e83 elementor-section-boxed elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"bab7e83\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-4d0a2c8 jltma-glass-effect-no\" data-id=\"4d0a2c8\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-inner-section elementor-element elementor-element-15a2d3d elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"15a2d3d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-491a86e jltma-glass-effect-no\" data-id=\"491a86e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-82c457b jltma-glass-effect-no elementor-widget elementor-widget-heading\" data-id=\"82c457b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Drug Discovery Services<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4eadd50 dalriada-side-menu elementor-nav-menu__text-align-aside jltma-glass-effect-no elementor-widget elementor-widget-nav-menu\" data-id=\"4eadd50\" data-element_type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;dropdown&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;i class=\\&quot;fas fa-angle-down\\&quot;&gt;&lt;\\\/i&gt;&quot;,&quot;library&quot;:&quot;fa-solid&quot;}}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<link rel=\"stylesheet\" href=\"https:\/\/dalriadatx.com\/wp-content\/plugins\/elementor-pro\/assets\/css\/widget-nav-menu.min.css\">\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-4eadd50\" class=\"elementor-nav-menu\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-1243\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/\" class=\"elementor-item\" tabindex=\"-1\">Concept to PDC  Discovery Programs<\/a>\n<ul class=\"sub-menu elementor-nav-menu--dropdown\">\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-1245\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/target-validation\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Target Validation<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-1244\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/hit-identification\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Hit Identification<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-1263\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/hit-to-lead\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Hit to Lead<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-1264\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/lead-optimization\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Lead Optimization<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2161\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/covalent-programs\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Covalent Programs<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2155\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/degrader-programs\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Degrader Programs<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2160\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/cannabinoid-programs\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Cannabinoid Programs<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-4092\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/psychedelic-programs\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Psychedelic Programs<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2156\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/nce-ip-creation-and-expansion\/\" class=\"elementor-sub-item\" tabindex=\"-1\">NCE IP Creation and Expansion<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2157\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/platform-technologies\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Platform Technologies<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2158\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/fast-follower\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Fast-Follower<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2159\"><a href=\"https:\/\/dalriadatx.com\/concept-to-pdc-discovery-programs\/therapeutic-areas\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Therapeutic Areas<\/a><\/li>\n<\/ul>\n<\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-581\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-strategy\/\" class=\"elementor-item\" tabindex=\"-1\">Turn-Key Discovery Strategy<\/a>\n<ul class=\"sub-menu elementor-nav-menu--dropdown\">\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2163\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-strategy\/program-design-execution\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Program Design &#038; Execution<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2172\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-strategy\/medicinal-chemistry\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Medicinal Chemistry<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2167\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-strategy\/in-vitro-pharmacology\/\" class=\"elementor-sub-item\" tabindex=\"-1\"><em>In Vitro<\/em> Pharmacology<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2171\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-strategy\/adme-and-dmpk\/\" class=\"elementor-sub-item\" tabindex=\"-1\">ADME and DMPK<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2168\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-strategy\/in-vivo-pharmacology\/\" class=\"elementor-sub-item\" tabindex=\"-1\"><em>In Vivo<\/em> Pharmacology<\/a><\/li>\n<\/ul>\n<\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2173\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-management\/\" class=\"elementor-item\" tabindex=\"-1\">Turn-Key Discovery Management<\/a>\n<ul class=\"sub-menu elementor-nav-menu--dropdown\">\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2174\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-management\/program-management\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Program Management<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2178\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-management\/sub-contracting-management\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Sub-Contracting Management<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2175\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-management\/controlled-substances\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Controlled Substances<\/a><\/li>\n<\/ul>\n<\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2179\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/\" class=\"elementor-item\" tabindex=\"-1\">Turn-Key Discovery Labs<\/a>\n<ul class=\"sub-menu elementor-nav-menu--dropdown\">\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-4087\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/chemistry\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Chemistry<\/a>\n\t<ul class=\"sub-menu elementor-nav-menu--dropdown\">\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2197\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/chemistry\/medicinal-chemistry\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Medicinal Chemistry<\/a><\/li>\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2196\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/chemistry\/synthetic-chemistry\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Synthetic Chemistry<\/a><\/li>\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2180\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/chemistry\/analytical-chemistry\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Analytical Chemistry<\/a><\/li>\n\t<\/ul>\n<\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-4091\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/in-vitro-biology\/\" class=\"elementor-sub-item\" tabindex=\"-1\"><em>In Vitro<\/em> Biology<\/a>\n\t<ul class=\"sub-menu elementor-nav-menu--dropdown\">\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2181\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/in-vitro-biology\/cell-and-molecular-biology\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Cell and Molecular Biology<\/a><\/li>\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2195\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/in-vitro-biology\/protein-production\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Protein Production<\/a><\/li>\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2194\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/in-vitro-biology\/biochemical-and-biophysical-assays\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Biochemical and Biophysical Assays<\/a><\/li>\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2193\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/in-vitro-biology\/crystallography\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Crystallography<\/a><\/li>\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-4084\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-strategy\/in-vitro-pharmacology\/ms-based-protein-assays\/\" class=\"elementor-sub-item\" tabindex=\"-1\">MS-Based Protein Assays<\/a><\/li>\n\t<\/ul>\n<\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-4086\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/dmpk\/\" class=\"elementor-sub-item\" tabindex=\"-1\">DMPK<\/a>\n\t<ul class=\"sub-menu elementor-nav-menu--dropdown\">\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2182\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/dmpk\/in-vitro-admet\/\" class=\"elementor-sub-item\" tabindex=\"-1\"><em>In Vitro<\/em> ADME(T)<\/a><\/li>\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2184\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/dmpk\/in-vivo-dmpk\/\" class=\"elementor-sub-item\" tabindex=\"-1\"><em>In-Vivo<\/em> DMPK<\/a><\/li>\n\t<\/ul>\n<\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-4088\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/cadd\/\" class=\"elementor-sub-item\" tabindex=\"-1\">CADD<\/a>\n\t<ul class=\"sub-menu elementor-nav-menu--dropdown\">\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2185\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/cadd\/docking\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Docking<\/a><\/li>\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2187\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/cadd\/model-development\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Model Development<\/a><\/li>\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2186\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/cadd\/in-silico-adme\/\" class=\"elementor-sub-item\" tabindex=\"-1\"><em>In Silico<\/em> ADME(T)<\/a><\/li>\n\t<\/ul>\n<\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-4085\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/proteomics\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Proteomics<\/a>\n\t<ul class=\"sub-menu elementor-nav-menu--dropdown\">\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2191\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/proteomics\/whole-proteome-profiling\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Whole-Proteome Profiling<\/a><\/li>\n\t\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2190\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/proteomics\/chemoproteomics\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Chemoproteomics<\/a><\/li>\n\t<\/ul>\n<\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-4089\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/custom-assays\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Custom Assays<\/a><\/li>\n\t<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-4090\"><a href=\"https:\/\/dalriadatx.com\/turn-key-discovery-labs\/biomarker-analysis\/\" class=\"elementor-sub-item\" tabindex=\"-1\">Biomarker Analysis<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-50ac373 jltma-glass-effect-no elementor-widget elementor-widget-heading\" data-id=\"50ac373\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">&nbsp;<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-7bdcd547 jltma-glass-effect-no\" data-id=\"7bdcd547\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a27c015 jltma-glass-effect-no elementor-widget elementor-widget-heading\" data-id=\"a27c015\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\"><em>In-Vivo<\/em> DMPK<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4cec1f4 jltma-glass-effect-no elementor-widget elementor-widget-text-editor\" data-id=\"4cec1f4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 26-03-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p><em>In vivo<\/em> DMPK and bioanalysis needs span hit-to-lead to clinical stages of discovery and development program. At Dalriada, we ensure\u00a0top quality data and insights to enable small molecule programs.<\/p><p>Our experienced bench-side team works with top-of-the-line instrumentation, including Waters\u00a0Xevo\u00a0G2-XS\u00a0Qtof, Sciex Triple Quad 5500+ coupled to Agilent 1290 Infinity II UHPLC, Sciex API 3000 triple quad, coupled to Agilent 1100\/Shimadzu HPLC.<\/p><p>Our\u00a0<strong><a href=\"\/turn-key-discovery-strategy\/\">Discovery Strategy<\/a><\/strong>\u00a0team is available to provide expert input for all in vivo DMPK and bioanalysis needs.<\/p><p>We support end-to-end design, management and execution of <em>in vivo<\/em> PK studies to enable discovery programs.\u00a0In-life portion of the PK studies is routinely sub-contracted to local reputable partner organizations to\u00a0cover the full range of dosing routes and species. In house, we conduct:<\/p><ul><li>Discovery formulation screening and development (solubility and stability)<\/li><li>Simple formulation for PO and IV dosing<\/li><li>Analytical Method development and qualification for PK bioanalysis<\/li><li>Quantitative analysis of samples with various biological matrices<\/li><li>Full management of <em>in vivo<\/em> portion of the studies<\/li><li>Tissue concentration measurements (brain, colon, bone marrow, etc.)<\/li><li>Quantitative and semi-quantitative measurements<\/li><li>Parent and metabolites analysis<\/li><\/ul><p><br \/>A broad scope of biomarker analyses from <em>in vivo<\/em> studies is further available at Dalriada.<\/p><p>Our\u00a0<a href=\"\/turn-key-discovery-labs\/dmpk\/\"><strong>ADME<\/strong><\/a>\u00a0team works side by side with the rest of the Discovery Labs team assigned to the project (including\u00a0<a href=\"\/turn-key-discovery-labs\/chemistry\/\"><strong>chemistry<\/strong><\/a>,\u00a0<a href=\"\/turn-key-discovery-labs\/cadd\/\"><strong>CADD<\/strong><\/a>,\u00a0<a href=\"\/turn-key-discovery-labs\/in-vitro-biology\/\"><strong><em>in vitro<\/em><\/strong><strong> biology<\/strong><\/a>,\u00a0<a href=\"\/turn-key-discovery-labs\/proteomics\/\"><strong>proteomics<\/strong><\/a>), and alongside our\u00a0<a href=\"\/turn-key-discovery-strategy\/\"><strong>Discovery Strategy<\/strong><\/a>\u00a0and\u00a0<a href=\"\/turn-key-discovery-management\/\"><strong>Discovery Management<\/strong><\/a>\u00a0teams, to unlock the fastest in the industry design-make-test-analyze cycles, accelerate troubleshooting, agilely execute, and actively and collaboratively drive innovation from the start.<\/p><p><a href=\"\/turn-key-model\/\"><strong>Learn more about our Turn-Key model here<\/strong><\/a>.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Turn-Key Discovery Labs\u200b Drug Discovery Services &nbsp; In-Vivo DMPK In vivo DMPK and bioanalysis needs span hit-to-lead to clinical stages of discovery and development program. At Dalriada, we ensure\u00a0top quality data and insights to enable small molecule programs. Our experienced bench-side team works with top-of-the-line instrumentation, including Waters\u00a0Xevo\u00a0G2-XS\u00a0Qtof, Sciex Triple Quad 5500+ coupled to Agilent [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":3498,"menu_order":64,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"folder":[],"_links":{"self":[{"href":"https:\/\/dalriadatx.com\/wp-json\/wp\/v2\/pages\/2135"}],"collection":[{"href":"https:\/\/dalriadatx.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/dalriadatx.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/dalriadatx.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/dalriadatx.com\/wp-json\/wp\/v2\/comments?post=2135"}],"version-history":[{"count":0,"href":"https:\/\/dalriadatx.com\/wp-json\/wp\/v2\/pages\/2135\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/dalriadatx.com\/wp-json\/wp\/v2\/pages\/3498"}],"wp:attachment":[{"href":"https:\/\/dalriadatx.com\/wp-json\/wp\/v2\/media?parent=2135"}],"wp:term":[{"taxonomy":"folder","embeddable":true,"href":"https:\/\/dalriadatx.com\/wp-json\/wp\/v2\/folder?post=2135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}